Kalyani, Adula published the artcilePalladium catalyzed nitrile insertion and cyanation of biindoles: Synthesis of indole fused α-carboline scaffolds via double C-H activation, SDS of cas: 100-70-9, the main research area is indole fused alpha carboline preparation; biindole nitrile double carbon hydrogen activation cyclization palladium.
A palladium-catalyzed synthesis of indole fused α-carbolines (pyridodiindoles) from 2,3′-biindoles and nitriles has been developed. This conversion involves the double C-H activation and cyclization of 2,3′-biindoles with nitriles via C-C and C-N bond formation in a single step. However, C-3 cyanated biindoles were formed through a retro-Mannich pathway when the reaction was carried out with Et cyanoacetate.
Tetrahedron Letters published new progress about C-H bond activation. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, SDS of cas: 100-70-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts