Tong, Yue published the artcilePhotocatalytic redox-neutral arylation of cyclopropanols with cyanoarenes via radical-mediated C-C and C-CN bond cleavage, Recommanded Product: Phthalonitrile, the main research area is cyclopropanol cyanoarene bond cleavage photocatalytic redox neutral arylation.
β-Arylated ketones widely exist in many biol. active mols. and natural products. Herein, we describe a photocatalytic redox-neutral arylation of cyclopropanols with cyanoarenes via radical-mediated C-C and C-CN bond cleavage to afford various β-arylated ketones. This mild and external oxidant-free approach showed good compatibility with a range of cyclopropanols and cyanoarenes and accomplished absolute regioselective control for the precise functionalization of pyridines via the C-CN bond cleavage of 4-cyanopyridines. Remarkably, this photocatalytic ring-opening of cyclopropanols was enabled by proton-coupled electron transfer (PCET) activation using an oxidized photocatalyst.
Organic Chemistry Frontiers published new progress about Arylation (neutral). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Recommanded Product: Phthalonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts