Gao, Zeng published the artcileBronsted Acid Catalyzed Cyclization of Inert N-Substituted Pyrroles to Benzo[ f ]pyrrolo[1,2-a][1,4]diazepines, HPLC of Formula: 1885-29-6, the main research area is benzopyrrolodiazepine preparation; substituted pyrrole tandem intramol dehydroxylation cyclization Bronsted Acid catalyzed; enantioselective preparation benzopyrrolodiazepine; pyrrolylphenyl methanamine chiral phosphoric acid catalyzed intermol addition.
Two approaches involving intramol. and intermol. cyclization, resp., were developed for the direct and practical construction of a series of important benzo[f]pyrrolo[1,2-a][1,4]azepines such as I [R = H, Me, Ph, etc.; R1 = H, Me, Cl] by using Bronsted acid catalysts. Upon catalysis by TsOH, the intramol. dehydroxylation/ring closure of 3-hydroxy-2-[2-(1 H-pyrrol-1-yl)benzyl]isoindolin-1-ones provided various racemic benzo[f]pyrrolo[1,2-a][1,4]azepines in high yields. Furthermore, enantioenriched benzo[f]pyrrolo[1,2-a][1,4]azepines II [R = H, Me; R1 = H, Cl; R2 = H, Cl, F] were also obtained by chiral phosphoric acid catalyzed intermol. addition of [2-(1 H-pyrrol-1-yl)phenyl]methanamines to 2-formylbenzoates under mild conditions.
Synlett published new progress about Addition reaction. 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, HPLC of Formula: 1885-29-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts