Muley, Arabinda published the artcileHigh phenoxazinone synthase activity of two mononuclear cis-dichloro cobalt(II) complexes with a rigid pyridyl scaffold, SDS of cas: 100-70-9, the main research area is crystal structure cobalt bipyridine triazolylpyridine chloro; cobalt bipyridine triazolylpyridine preparation phenoxazinone synthase activity.
Phenoxazinone synthase (PHS) is a pentanuclear Cu enzyme studied for the last two decades, and though both Mn and Cu complexes were explored extensively, there are only a handful of reports on Co mononuclear moieties. In this regard, the authors have successfully synthesized two cis dichloro Co(II) mononuclear complexes Co(bpy)2Cl2:[1] and Co(L1)2Cl2:[2] with polypyridyl ligands (bpy = 2,2′-bipyridine, L1 = 2,2′-(1-methyl-1H-1,2,4-triazole-3,5-diyl)dipyridine) and thoroughly characterized them by different spectroscopic and anal. techniques such as FTIR, 1H NMR, UV-visible spectroscopy and ESI mass spectra. The mol. structures of 1 and 2 are elucidated by single-crystal x-ray diffraction studies. Spectral properties and redox behavior for 1-2 were examined The complexes show phenoxazinone synthase activity under ambient conditions and thorough examination of the acquired spectroscopic data imply excellent reactivity for both. Kinetic parameters for both the complexes are evaluated and the turnover numbers (kcat value) of these two complexes are 201.24 h-1 and 249.57 h-1 for 1 and 2, resp., which are quite high compared to those of previously reported similar complexes. The possible mechanistic route is also established with the help of mass spectroscopy and titrimetric anal. was performed to detect H2O2 that is a key intermediate formed in the catalysis and thus to prove the involvement of O2 in the oxidation This report offers an in-depth summary of metal ion involvement and the extent of the phenoxazinone synthase activity.
New Journal of Chemistry published new progress about Crystal structure. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, SDS of cas: 100-70-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts