Carpenter, K. published the artcileHerbicidal activity of halogenohydroxybenzonitriles, SDS of cas: 3336-34-3, the publication is Mededelingen van de Landbouwhogeschool en de Opzoekingsstations van de Staat te Gent (1964), 29(3), 644-54, database is CAplus.
The activities of analogs of ioxynil (4-hydroxy-3,5-diiodobenzonitrile) (I) were compared in greenhouse experiments I applied in amounts of 0.25 kg./ha. to the leaves of seedlings, kills weed spp. belonging to the Compositae, Cruciferae, Chenopodiaceae, Polygonaceae, and Caryophyllaceae families. Replacement of one or both of the iodine atoms in I by Cl or Br influences the herbicidal spectrum, but not the general level of herbicidal activity as determined in the greenhouse. However, the number of halogens introduced and their positions in the nucleus are both critical, since the peak of activity occurs with dihalogenation in the 3- and 5-positions. Conversion of the CN group into either a CONH2 or COOH group and changes in the position of the OH group are all detrimental to activity. Acetylation of the OH group results in no loss of activity, but methylation causes some reduction in the herbicidal activity.
Mededelingen van de Landbouwhogeschool en de Opzoekingsstations van de Staat te Gent published new progress about 3336-34-3. 3336-34-3 belongs to nitriles-buliding-blocks, auxiliary class Chloride,Nitrile,Benzene,Phenol, name is 2,6-Dichloro-3-hydroxybenzonitrile, and the molecular formula is C7H3Cl2NO, SDS of cas: 3336-34-3.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts