Carpenter, K.’s team published research in Mededelingen van de Landbouwhogeschool en de Opzoekingsstations van de Staat te Gent in 29 | CAS: 3336-34-3

Mededelingen van de Landbouwhogeschool en de Opzoekingsstations van de Staat te Gent published new progress about 3336-34-3. 3336-34-3 belongs to nitriles-buliding-blocks, auxiliary class Chloride,Nitrile,Benzene,Phenol, name is 2,6-Dichloro-3-hydroxybenzonitrile, and the molecular formula is C7H3Cl2NO, Name: 2,6-Dichloro-3-hydroxybenzonitrile.

Carpenter, K. published the artcileHerbicidal activity of halo hydroxybenzonitriles, Name: 2,6-Dichloro-3-hydroxybenzonitrile, the publication is Mededelingen van de Landbouwhogeschool en de Opzoekingsstations van de Staat te Gent (1964), 29(3), 644-54, database is CAplus.

The activity of 37 specified analogs of the new herbicide ioxynil (4-hydroxy-3,5-diiodobenzonitrile) are compared in greenhouse screening experiments Ioxynil, applied to the leaves of seedlings, kills weed species belonging to the Compositae, Cruciferae, Chenopodiaceae, Polygonaceae, and Caryophyllaceae families. Replacement of one or both of the I atoms in ioxynil by Cl or Br influences the herbicidal spectrum but not the general level of herbicidal activity. However, the number of halogens introduced and their positions in the nucleus are both critical, since the peak of activity occurs with dihalogenation in the 3 and 5 positions. Conversion of the nitrile group into either the amide or carboxyl group and changes in the position of the hydroxyl group are all detrimental to activity. Acetylation of the hydroxyl group results in no loss of activity, but methylation causes some reduction of the herbicidal activity.

Mededelingen van de Landbouwhogeschool en de Opzoekingsstations van de Staat te Gent published new progress about 3336-34-3. 3336-34-3 belongs to nitriles-buliding-blocks, auxiliary class Chloride,Nitrile,Benzene,Phenol, name is 2,6-Dichloro-3-hydroxybenzonitrile, and the molecular formula is C7H3Cl2NO, Name: 2,6-Dichloro-3-hydroxybenzonitrile.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts