Trost, Barry M.’s team published research in Angewandte Chemie, International Edition in 51 | CAS: 5153-73-1

Angewandte Chemie, International Edition published new progress about 5153-73-1. 5153-73-1 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Alkenyl,Nitro Compound,Benzene, name is (E)-4-(2-Nitrovinyl)benzonitrile, and the molecular formula is C30H24BrCuN2P, Formula: C9H6N2O2.

Trost, Barry M. published the artcileHighly Stereoselective Synthesis of α-Alkyl-α-Hydroxycarboxylic Acid Derivatives Catalyzed by a Dinuclear Zinc Complex, Formula: C9H6N2O2, the publication is Angewandte Chemie, International Edition (2012), 51(26), 6480-6483, S6480/1-S6480/101, database is CAplus and MEDLINE.

The authors describe a highly diastereo- and enantioselective nitro-Michael reaction of 5H-oxazol-4-ones. The process provides a range of highly functionalized α-alkyl-α-hydroxycarboxylic acid derivatives in high yields. For example, reacting β-nitrostyrene with methyloxazolone I gave the desired product II in 95% yield (d.r. = 15.6:1, 88% ee) in the presence of ZnEt2 and phenol ligand III.

Angewandte Chemie, International Edition published new progress about 5153-73-1. 5153-73-1 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Alkenyl,Nitro Compound,Benzene, name is (E)-4-(2-Nitrovinyl)benzonitrile, and the molecular formula is C30H24BrCuN2P, Formula: C9H6N2O2.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts