Wang, Ming-Zhong published the artcileDesign, synthesis and antifungal activities of novel pyrrole alkaloid analogs, Application of 2-(Chloromethyl)benzonitrile, the publication is European Journal of Medicinal Chemistry (2011), 46(5), 1463-1472, database is CAplus and MEDLINE.
A series of novel analogs of pyrrole alkaloids were designed and synthesized by a facile method and their structures were characterized by 1H NMR, 13C NMR and high-resolution mass spectrometry (HRMS). The structure of compound I was identified by 2D NMR including heteronuclear multiple-quantum coherence (HMQC), heteronuclear multiple-bond correlation (HMBC) and H-H correlation spectrometry (H-H COSY) spectra. Their antifungal activities against five fungi were evaluated, and the results indicated that some of the title compounds showed moderate fungicidal activities in vitro against Alternaria solani, Cercospora arachidicola, Fusarium omysporum, Gibberella zeae and Physalospora piricola at the dosage of 50 μg mL-1. Compound I and its dibromo derivative exhibited good activities against P. piricola at low dosage.
European Journal of Medicinal Chemistry published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C23H28N2O4, Application of 2-(Chloromethyl)benzonitrile.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts