Zhan, Peng published the artcileSynthesis and anti-HIV activity of novel 2,4-disubstituted-7-methyl-1,1,3-trioxo-2H,4H-pyrazolo[4,5-e][1,2,4]thiadiazine derivatives, Name: 2-(Chloromethyl)benzonitrile, the publication is Drug Discoveries & Therapeutics (2011), 5(6), 279-285, database is CAplus and MEDLINE.
Sixteen 2,4-dibenzyl-substituted 7-methyl-1,1,3-trioxo-2H,4H-pyrazolo[4,5-e][1,2,4]thiadiazines (PTDs) were prepared by a facile 1-pot reaction starting from 7-methyl-pyrazolo[4,5-e][1,2,4]thiadiazine and two different benzyl halides. The structures of all synthesized compounds were confirmed by 1H- and 13C-NMR, IR spectra (IR) and mass spectra (MS). Anti-HIV activity was evaluated and none of the compounds inhibit HIV replication in human T-lymphocyte (MT-4) cell culture.
Drug Discoveries & Therapeutics published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C9H9ClN2, Name: 2-(Chloromethyl)benzonitrile.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts