A simple route to N-(2-hydroxyarylidene)nitroanilines, versatile synthons for coumarins was written by Czerney, P.;Hartmann, H.. And the article was included in Journal fuer Praktische Chemie (Leipzig) in 1982.Application of 51473-74-6 This article mentions the following:
RCH:NC6H4NO2 (R = 4-amino-2-hydroxyphenyl, 1-hydroxy-2-naphthyl, 2-hydroxy-1-naphthyl) were prepared by treating the phenols with HC(OEt)3 and H2NC6H4NO2. RCH:NC6H4NO2 form B complexes and cyclized with R1CH2CO2Et or R1CH2CN (R1 = Ac, cyano, COCH2CO2Et, CONH2, 2-benzimidazolyl, 4-O2NC6H4, 4-phenyl-2-thiazolyl) to give the coumarins I (R2 = H, R3 = 7-NMe2, 7-pyrrolidino, 7-piperidino, 7-NEt2; R2R3 = 5,6-CH:CHCH:CH, 7,8-CH:CHCH:CH). In the experiment, the researchers used many compounds, for example, 7-(Diethylamino)-2-oxo-2H-chromene-3-carbonitrile (cas: 51473-74-6Application of 51473-74-6).
7-(Diethylamino)-2-oxo-2H-chromene-3-carbonitrile (cas: 51473-74-6) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Application of 51473-74-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts