Organophosphorus compounds with β-cyanoethyl-type structural components. I. Synthesis of β-cyanoethylated amidophosphites and phosphoramides was written by Petrov, Pavel;Vlad, Florin-Iosif;Muresan, Sorel;Valceanu, Radu. And the article was included in Revista de Chimie (Bucharest) in 1995.Electric Literature of C9H12N4 This article mentions the following:
This paper presents three types of phosphorylation reactions for mixtures of NH(CH2CH2CN)2 with N(CH2CH2CN)3, obtained by nucleophilic addition reaction of NH3 to acrylonitrile. Thus, reaction of 10 equiv (MeO)2P(O)H with a 10:1 mixture of the above amines in PhMe containing CCl4 and Et3N gave (MeO)2P(O)N(CH2CH2CN)2. Reaction of 4 equiv PCl3 or P(O)Cl3 with a 21:3 mixture of the amines in dichloroethane gave P[N(CH2CH2CN)2]3 or P(O)[N(CH2CH2CN)2]3, resp. In the experiment, the researchers used many compounds, for example, 3,3′,3”-Nitrilotripropanenitrile (cas: 7528-78-1Electric Literature of C9H12N4).
3,3′,3”-Nitrilotripropanenitrile (cas: 7528-78-1) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. Asymmetric bioreduction of nitriles is an attractive route to produce optically active nitriles as current metal-catalyzed hydrogenations tend to have low reactivity.Electric Literature of C9H12N4
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts