Ketimines. III. ω-Cyclohexylalkyl alkyl type was written by Pickard, P. L.;Young, C. W.. And the article was included in Journal of the American Chemical Society in 1951.Product Details of 4435-14-7 This article mentions the following:
In this abstract, R = cyclohexyl throughout.) Acid chlorides, R(CH2)XCl (read x, yield (%), b.p., d423, nD20): 3, 92.5, b1 83°, 1.0175, 1.4710; 5, 96, b1 106°, 0.9987, 1.4714. Slow addition of the acid chlorides to NH4OH at 0° and crystallization of the precipitate from MeOH-H2O gave above 80% of the amides, R(CH2)3CONH2: × = 3, m. 111°; 5, m. 117°. Dehydration with excess POCl3 gave the nitriles, R(CH2)xCN (read x, yield (%), b.p., d420, nD20): 1, 70, b1 57°. 0.9180, 1.4575; 2, 80, b1 71°, 0.9107, 1.4602; 3, 83, b1 82°, 0.9056, 1.4607; 4, 85, b1 93°, 0.8950, 1.4618; 5, 86, b1 112°, 0.9879, 1.4637. The ketimines, R(CH2)x C(:NH)CHMeEt were prepared from 0.25 mole MeEtCHBr and 0.20 mole nitrile by the method of Pickard and Vaughan (C.A. 45,381 1a) (read x, yield (%), b.p., d420, and nD20): 2, 56, b2 101°, 0.8680, 1.4689; 3, 43, b1 107°, 0.8611, 1.4699; 4, 45, b1 121°, 0.8754, 1.4700; 5, 60, b1 130°, 0.8808, 1.4719. In the experiment, the researchers used many compounds, for example, 2-Cyclohexylacetonitrile (cas: 4435-14-7Product Details of 4435-14-7).
2-Cyclohexylacetonitrile (cas: 4435-14-7) belongs to nitriles. Nitriles are polar, as indicated by high dipole moments. As liquids, they have high relative permittivities, often in the 30s. Nitriles are susceptible to hydrogenation over diverse metal catalysts. The reaction can afford either the primary amine (RCH2NH2) or the tertiary amine ((RCH2)3N), depending on conditions.Product Details of 4435-14-7
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts