Ruthenium(II) bis(hydrazone) complexes derived from 1,3,4-oxadiazoles: Synthesis, crystal structure and catalytic application in N-alkylation reactions was written by Prakash, Govindan;Ramachandran, Rangasamy;Nirmala, Muthukumaran;Viswanathamurthi, Periasamy;Sanmartin, Jesus. And the article was included in Inorganica Chimica Acta in 2015.Electric Literature of C14H12N2 This article mentions the following:
1,3,4-Oxadiazoles (A-C) were derived via a series of reactions between isoniazid and salicylaldehydes. While reacting the oxadiazoles with [RuHCl(CO)(PPh3)3] in the presence of NaOH, mononuclear ruthenium(II) complexes bearing ‘salen’ type N,N’-bis(salicylidene)hydrazone ligands (1–3) were obtained. The oxadiazoles and ruthenium(II) complexes were characterized by anal. and spectral methods. The single crystal XRD analyses of complexes 1 and 2 suggested an octahedral geometry around ruthenium(II) ions in which the bis(hydrazone) act as mononeg. bidentate ligands. Also the presence of an intramol. hydrogen bonding between the hydroxyl proton and one of the azomethine nitrogens in all the complexes. Further, the complexes were proved as versatile catalysts for the N-alkylation of amines with alcs. under optimized reaction conditions. In the experiment, the researchers used many compounds, for example, 4-(Benzylamino)benzonitrile (cas: 10282-32-3Electric Literature of C14H12N2).
4-(Benzylamino)benzonitrile (cas: 10282-32-3) belongs to nitriles. Trimerization of aromatic nitriles requires harsh reaction conditions, high temperatures, long reaction times, and pressure. Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. Both routes are green in the sense that they do not generate stoichiometric amounts of salts.Electric Literature of C14H12N2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts