Palladium-catalyzed amination of aryl bromides using temperature-controlled microwave heating was written by Wan, Yiqian;Alterman, Mathias;Hallberg, Anders. And the article was included in Synthesis in 2002.HPLC of Formula: 10282-32-3 This article mentions the following:
Fast Pd-catalyzed aminations of aryl bromides were conducted in a non-inert reaction medium with temperature-controlled microwave heating. With a reaction time of 4 min at 130° or 180°, both electron-rich and electron-deficient aryl bromides reacted with various amines to provide fair to good yields of the corresponding secondary and tertiary anilines. As an example the amination of 4-bromobenzonitrile with imidazole is presented. In the experiment, the researchers used many compounds, for example, 4-(Benzylamino)benzonitrile (cas: 10282-32-3HPLC of Formula: 10282-32-3).
4-(Benzylamino)benzonitrile (cas: 10282-32-3) belongs to nitriles. The electronic structure of nitriles is very similar to that of an alkyne with the main difference being the presence of a set of lone pair electrons on the nitrogen. Asymmetric bioreduction of nitriles is an attractive route to produce optically active nitriles as current metal-catalyzed hydrogenations tend to have low reactivity.HPLC of Formula: 10282-32-3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts