Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles. [Erratum to document cited in CA152:074962] was written by Bakunov, Stanislav A.;Bakunova, Svetlana M.;Wenzler, Tanja;Ghebru, Maedot;Werbovetz, Karl A.;Brun, Reto;Tidwell, Richard R.. And the article was included in Journal of Medicinal Chemistry in 2011.Application In Synthesis of 3-Amino-4-methoxybenzonitrile This article mentions the following:
On page 270, in the left column, the Acknowledgment section was incomplete, and should read: “This work was supported by The Bill and Melinda Gates Foundation and NIH Grant 5U01AI075641.”. In the experiment, the researchers used many compounds, for example, 3-Amino-4-methoxybenzonitrile (cas: 60979-25-1Application In Synthesis of 3-Amino-4-methoxybenzonitrile).
3-Amino-4-methoxybenzonitrile (cas: 60979-25-1) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Application In Synthesis of 3-Amino-4-methoxybenzonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts