Cobalt-catalyzed asymmetric hydrogenation of ketones: A remarkable additive effect on enantioselectivity was written by Du, Tian;Wang, Biwen;Wang, Chao;Xiao, Jianliang;Tang, Weijun. And the article was included in Chinese Chemical Letters in 2021.Related Products of 101219-69-6 This article mentions the following:
A chiral cobalt pincer complex, when combined with an achiral electron-rich mono-phosphine ligand, catalyzes efficient asym. hydrogenation of a wide range of aryl ketones, affording chiral alcs. with high yields and moderate to excellent enantioselectivities (29 examples, up to 93% ee). Notably, the achiral mono-phosphine ligand showed a remarkable effect on the enantioselectivity of the reaction. In the experiment, the researchers used many compounds, for example, (R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6Related Products of 101219-69-6).
(R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6) belongs to nitriles. There has been no report on the microbial biosynthesis of nitriles and the physiological function of such enzymes, nor was it not even known whether aliphatic and aromatic nitriles are biological compounds or just petrochemicals. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Related Products of 101219-69-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts