Cyanobenzyl sulfates as alkylating agents. Alkylation of amines with bis(cyanobenzyl)sulfate was written by Grochowski, E.;Boleslawska, T.. And the article was included in Bulletin de l’Academie Polonaise des Sciences, Serie des Sciences Chimiques in 1972.HPLC of Formula: 37812-51-4 This article mentions the following:
(2-NCC6H4CH2)2SO4 (I) and (4-NCC6H4CH2)2SO4 (II) are powerful alkylating agents for amines. Thus the resp. mono-(cyanobenzyl) derivatives were obtained in 95-8% yield by treating I with morpholine or pyridine or treating II with PhNH2, PhCH2NH2, cyclohexylamine, morpholine, or pyridine. II was prepared in 68% yield from 4-NCC6H4CH2Br and Ag2SO4. Reaction of I with primary amines gave iminoisoindoles, however. In the experiment, the researchers used many compounds, for example, 4-(Morpholinomethyl)benzonitrile (cas: 37812-51-4HPLC of Formula: 37812-51-4).
4-(Morpholinomethyl)benzonitrile (cas: 37812-51-4) belongs to nitriles. Nitriles are polar, as indicated by high dipole moments. As liquids, they have high relative permittivities, often in the 30s. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).HPLC of Formula: 37812-51-4
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts