Copper-Catalyzed Enantioselective Hydrosilylation of Ketones by Using Monodentate Binaphthophosphepine Ligands was written by Junge, Kathrin;Wendt, Bianca;Addis, Daniele;Zhou, Shaolin;Das, Shoubhik;Beller, Matthias. And the article was included in Chemistry – A European Journal in 2010.Formula: C9H9NO This article mentions the following:
The first copper-catalyzed asym. hydrosilylation of carbonyl compounds by using chiral monodentate ligands is presented. Under comparably mild conditions, high yields and enantioselectivities (up to 96% ee) are achieved for a broad range of carbonyl compounds such as aryl alkyl, cyclic, heterocyclic and aliphatic ketones. Compared to other known asym. hydrosilylation catalysts, advantageously no base or fluoride activation is necessary. In the experiment, the researchers used many compounds, for example, (R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6Formula: C9H9NO).
(R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6) belongs to nitriles. Nitrile compounds can be prepared by the incorporation of a cyanide source through C–C bond formation or by dehydration of primary carboxamides. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Formula: C9H9NO
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts