One pot synthesis of fused pyrimidines from 2-[N-(methylthiothiocarbonyl)amino]acetate was written by Chowdhury, A. Z. M. Shaifullah;Shibata, Yasuyuki;Morita, Masatoshi;Kaya, Kunimitsu;Sano, Tomoharu. And the article was included in Heterocycles in 2001.Recommanded Product: 70291-62-2 This article mentions the following:
A variety of 3-substituted fused pyrimidines are readily obtained from the 2-amino esters with 2-[N-(methylthiothiocarbonyl)amino]acetate (I). Condensed imidazo[1,2-c]pyrimidine ring system was also constructed in a one-pot process by reacting heteroaromatic 2-amino nitriles with I, obtaining a number of novel tri- and tetracyclic compounds In the experiment, the researchers used many compounds, for example, 2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonitrile (cas: 70291-62-2Recommanded Product: 70291-62-2).
2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonitrile (cas: 70291-62-2) belongs to nitriles. Nitriles are polar, as indicated by high dipole moments. As liquids, they have high relative permittivities, often in the 30s. Alkyl nitriles are sufficiently acidic to undergo deprotonation of the C-H bond adjacent to the CN group.Strong bases are required, such as lithium diisopropylamide and butyl lithium. The product is referred to as a nitrile anion. Recommanded Product: 70291-62-2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts