ZIF-8 nanoparticles as an efficient and reusable catalyst for the Knoevenagel synthesis of cyanoacrylates and 3-cyanocoumarins was written by Kolmykov, Oleksii;Chebbat, Nassima;Commenge, Jean-Marc;Medjahdi, Ghouti;Schneider, Raphael. And the article was included in Tetrahedron Letters in 2016.Related Products of 51473-74-6 This article mentions the following:
Zeolitic imidazolate framework (ZIF-8) particles with an average size of ca. 355 nm and a sp. surface area of 1786 m2.g-1 were used as an heterogenous catalyst for the Knoevenagel synthesis of α,β-unsaturated cyanoesters and 3-cyanocoumarins. The preparation of 3-cyanocoumarins was efficiently achieved using DMF as the solvent and conducting the condensation at 80°. When the reaction was performed in ethanol, only the intermediates α,β-unsaturated cyanoesters were obtained. The ZIF-8 catalyst could be reused up to five times without any degradation in activity. SEM and XRD analyses demonstrated the high stability of ZIF-8 crystals during the recycling test. In the experiment, the researchers used many compounds, for example, 7-(Diethylamino)-2-oxo-2H-chromene-3-carbonitrile (cas: 51473-74-6Related Products of 51473-74-6).
7-(Diethylamino)-2-oxo-2H-chromene-3-carbonitrile (cas: 51473-74-6) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. Nitriles are susceptible to hydrogenation over diverse metal catalysts. The reaction can afford either the primary amine (RCH2NH2) or the tertiary amine ((RCH2)3N), depending on conditions.Related Products of 51473-74-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts