Synthesis and properties of several nitrile analogs of bis(2-chloroethyl)amine was written by Rodionov, P. V.;Rapp, L. B.;Nikolaeva, S. V.. And the article was included in Fiziologicheski Aktivnye Veshchestva (1966-1992) in 1973.Recommanded Product: 7528-78-1 This article mentions the following:
Reaction of RN(CH2CH2Cl)2 (R = NCCH2CH2, m-BrC6H4CH2, p-FC6H4CH2, m-, p-, and o-MeC6H4CH2) with NaCN-EtOH gave a mixture of RN(CH2CH2CN)2 and RN(CH2CH2CN)CH2CH2OEt. The LD50 of (NCCH2CH2)3N in mice (s.c.) was 880 mg/kg; the maximum transfer dose was 300 mg/kg. In the experiment, the researchers used many compounds, for example, 3,3′,3”-Nitrilotripropanenitrile (cas: 7528-78-1Recommanded Product: 7528-78-1).
3,3′,3”-Nitrilotripropanenitrile (cas: 7528-78-1) belongs to nitriles. There has been no report on the microbial biosynthesis of nitriles and the physiological function of such enzymes, nor was it not even known whether aliphatic and aromatic nitriles are biological compounds or just petrochemicals. Nitriles are susceptible to hydrogenation over diverse metal catalysts. The reaction can afford either the primary amine (RCH2NH2) or the tertiary amine ((RCH2)3N), depending on conditions.Recommanded Product: 7528-78-1
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts