A strategy of two-step tandem catalysis towards direct N-alkylation of nitroarenes with ethanol via facile fabricated novel Co-based catalysts derived from coordination polymers was written by Wang, Jing;Qi, Tianqinji;Li, Zhibin;She, Wei;Li, Xuewei;Li, Jingfang;Yan, Pengfei;Li, Weizuo;Li, Guangming. And the article was included in Journal of Catalysis in 2019.Computed Properties of C9H10N2 This article mentions the following:
Three novel N-doped carbon supported Co/Co3O4 catalysts, namely, Co@CN-hmta, Co@CN-larg and Co-Co3O4@CN-bipy, with sheet-, worm-, honeycomb-like morphologies resp., have been fabricated by the pyrolysis of well-defined coordination polymers (CPs). Base upon the application of as-prepared catalysts, for the reaction of N-alkylation of nitroarenes 4-RC6H4NO2 (R = H, 3-Cl, 4-Me, etc.) with ethanol, a direct two-step tandem reaction is realized, in which Co@CN-hmta delivers 100% conversion/selectivity of N-ethylaniline/N,N-diethylaniline from the direct N-alkylation of nitroarenes with ethanol. The kinetic studies were conducted to confirm that the N-alkylation of aniline with ethanol is the rate-determining step in the two-step tandem reaction. The SEM/EDX, XRD, Raman, TEM, XPS, and CO2-TPD characterization results have revealed that sizes and dispersion of metallic Co, amount of structural defects and surface Lewis basicity towards three catalysts can be tuned by changing the structures of Co-based CPs designed by different organic linkers, which may also help to understand the preparation of industrial catalysts on a mol. level. The optimized Co@CN-hmta catalyst is easily recycled by using the external magnet for successive reuses without any loss in both activity and selectivity. This is the first reported carbon-nitrogen species supported Co/Co3O4 catalysts derived from the CPs, which could effectively catalyze the N-alkylation of nitroarenes with ethanol to produce the secondary amines and/or tertiary amines. This low-cost, recyclable and easy scale-up N-doped carbon supported catalyst may be of potential application in various heterogeneous catalytic reactions. In the experiment, the researchers used many compounds, for example, 4-(Ethylamino)benzonitrile (cas: 4714-63-0Computed Properties of C9H10N2).
4-(Ethylamino)benzonitrile (cas: 4714-63-0) belongs to nitriles. Nitrile compounds can be prepared by the incorporation of a cyanide source through C–C bond formation or by dehydration of primary carboxamides. Alkyl nitriles are sufficiently acidic to undergo deprotonation of the C-H bond adjacent to the CN group.Strong bases are required, such as lithium diisopropylamide and butyl lithium. The product is referred to as a nitrile anion. Computed Properties of C9H10N2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts