Mohsenzadeh, Farshid’s team published research in Research on Chemical Intermediates in 2020-12-31 | CAS: 1885-29-6

Research on Chemical Intermediates published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, COA of Formula: C7H6N2.

Mohsenzadeh, Farshid published the artcileNaturally occurring organic acids for organocatalytic synthesis of pyrroles via Paal-Knorr reaction, COA of Formula: C7H6N2, the main research area is pyrrole Paal Knorr synthesis aniline hexanedione oxalic acid catalysis.

In this study, common naturally occurring organic acids, namely oxalic, malonic, succinic, tartaric and citric acid (as safe, inexpensive, and biodegradable organocatalysts), have been employed for Paal-Knorr pyrrole synthesis. The organocatalyzed reaction proved to be effective in ethanol at 60°C. However, the reaction rate is mainly dominated by the nature and position of functional groups on the aromatic ring of substrate. This metal-free procedure tolerates a series of functional groups and should be considered as an asset to the pharmaceutical industry since no metal contamination could take place during the synthesis of pyrrole scaffolds.

Research on Chemical Intermediates published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, COA of Formula: C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts