Wolinska, Ewa published the artcileSynthesis and structures of three new pyridine-containing oxazoline ligands of complexes for asymmetric catalysis, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is pyridine oxazoline ligand crystal structure asym catalysis; DFT calculations; Hirshfeld surface analysis; asymmetric catalysis; crystal structure; oxazoline ligand.
Three new chiral pyridine-containing oxazoline derivatives with fluorine and perfluoromethyl groups, namely, 2-({2-[(4S)-4-phenyl-4,5-dihydro-1,3-oxazol-2-yl]phenyl}amino)-5-(trifluoromethyl)pyridine, C21H16F3N3O, 2-({5-fluoro-2-[(4S)-4-isopropyl-4,5-dihydro-1,3-oxazol-2-yl]phenyl}amino)-5-(trifluoromethyl)pyridine, C18H17F4N3O, and 2-({2-[(3aR,8aS)-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-2-yl]phenyl}amino)-5-(trifluoromethyl)pyridine, C22H16F3N3O, as chiral ligands in metal-catalyzed asym. reactions, were synthesized and characterized by spectral and X-ray diffraction methods. The conformation of the mols. is influenced by strong N-H···N hydrogen bonding and weak C-H···X (X = O and N) interactions. There are no intermol. hydrogen bonds in the crystal structures of the analyzed compounds Hirshfeld surface anal. showed that the H···H contacts constitute a high percentage of the intermol. interactions. The conformational anal. was performed by theor. calculations using the d. functional theory (DFT) method. The mechanism of complex formation in terms of the electron-withdrawing effect of the substituents on the oxazoline ring and the ligand conformation is discussed.
Acta Crystallographica, Section C: Structural Chemistry published new progress about Addition reaction catalysts, stereoselective. 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts