Wrzeszcz, Zuzanna published the artcileHeteroaromatic N-oxides modified with a chiral oxazoline moiety, synthesis and catalytic applications, SDS of cas: 100-70-9, the main research area is oxazoline chiral heteroaromatic nitrogen oxide preparation stereoselective catalytic reaction; heteroaromatic oxide preparation oxidation amino alc heterocyclization.
A multi-step synthesis of a series of chiral oxazoline substituted pyridine N-oxides I (R1 = i-pr, t-bu, Ph; R2 = H; R1 = R2 = indane, trimethyl-bicyclo[2.2.1]heptane), alkyl derived of pyridine N-oxides II, bipyridine N-oxides III, and isoquinoline N-oxides IV, based on amino alcs. R1(NH2)HC-CH(OH)R2 derived from natural amino acids or other previously prepared, is presented herein. Various synthetic pathways have been designed and tested according to the properties and limitations imposed by the target products. The encountered problems related to the stability of the products were discussed. The resulting compounds (eighteen structures) were tested as catalysts in the allylation of benzaldehyde (obtaining up to 79% ee) as well as in nitroaldol reaction (obtaining up to 48% ee).
Catalysts published new progress about Allylation catalysts, stereoselective. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, SDS of cas: 100-70-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts