Adding a certain compound to certain chemical reactions, such as: 6629-04-5, name is N-Cyanoacetylurethane, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6629-04-5, Application In Synthesis of N-Cyanoacetylurethane
Take 15.0 of aniline, 90mL of concentrated hydrochloric acid, and 200mL of water to dissolve it.The solution is cooled below 0 C,A 70 mL aqueous solution containing 13.4 g of sodium nitrite was added dropwise,During the dropwise addition, keep the temperature below 0 C. After the dropwise addition is completed, keep warm and stir for 0.5h.Add 400 mL of ethanol to dissolve2-cyano-2-acetyl urethane 26.4gIt was incubated with a mixture of anhydrous sodium acetate 39.7 for 3 h.The solid precipitated in the reaction mixture was filtered, and the filter cake was washed with water.dryGot a pale yellow product,Intermediate[2-cyano-2- (2-phenylhydradino) acetyl] urethane(h).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, N-Cyanoacetylurethane, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Liaoning University; Liu Ju; Chen Ye; Li Chunyan; Ding Shi; Gong Yilin; Shi Jiantao; Hao Xuechen; Wang Zhen; Yang Yaxing; (23 pag.)CN110684013; (2020); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts