Singh, Shivendra published the artcileRapid access of 2,3,4-trisubstituted-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole derivatives via one-pot three component catalytic reaction, Synthetic Route of 5153-73-1, the publication is Tetrahedron Letters (2012), 53(45), 6087-6090, database is CAplus.
A simple, green, and efficient one-pot three component strategy for the synthesis of 2-aryl-3-nitro-4-hydroxy-2,3,4,9-tetrahydrothiopyrano[2,3-b]indoles I [R = Boc, EtO2C; R1 = Ph, 4-MeC6H4, 2-ClC6H4, etc.; R2 = H, Me] has been achieved by the combination of N-protected-2-chloro-3-formylindoles, sodium hydrosulfide with β-nitrostyrenes R1CH:C(R2)NO2 at room temperature in ethanol using DABCO as a catalyst. Furthermore, high enantio- and diastereoselectives’ syntheses of title compounds have been achieved for the first time using cupreidine (5 mol %) as catalyst, providing good to excellent yields.
Tetrahedron Letters published new progress about 5153-73-1. 5153-73-1 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Alkenyl,Nitro Compound,Benzene, name is (E)-4-(2-Nitrovinyl)benzonitrile, and the molecular formula is C10H15ClO3S, Synthetic Route of 5153-73-1.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts