Li, Zhi published the artcileSeparation of chiral cyanohydrin enantiomers by gas chromatography, Application In Synthesis of 13312-84-0, the publication is Fenxi Huaxue (1997), 25(6), 708-713, database is CAplus.
The enantiomers of 14 cyanohydrins were separated on permethylated β-cyclodextrin column (fused silica, 25 m × 0.22 mm) by derivatization. The acetyl chloride and trifluoroacetic anhydride were used as derivatization reagents. All racemates were separated to baseline with separation factors (α) = 1.02-1.13. The enantiomer excess values of some enantiomers from asym. synthesis samples were determined, and they were identical with those by optical purity and HPLC methods. The separation effect of the two derivatization methods and the separation mechanism of enantiomers are discussed.
Fenxi Huaxue published new progress about 13312-84-0. 13312-84-0 belongs to nitriles-buliding-blocks, auxiliary class Chloride,Nitrile,Benzene,Alcohol,Benzene Compounds, name is 2-(2-Chlorophenyl)-2-hydroxyacetonitrile, and the molecular formula is C8H6ClNO, Application In Synthesis of 13312-84-0.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts