Conformational preferences of some substituted methyl groups in cyclohexanes as studies by carbon-13 nuclear magnetic resonance was written by Kitching, William;Olszowy, Henry;Adcock, William. And the article was included in Organic Magnetic Resonance in 1981.SDS of cas: 4435-14-7 This article mentions the following:
Low-temperature 13C NMR spectra of 80:20 mixtures of the cis and trans isomers of the disubstituted cyclohexanes I (R = Br, cyano, OH, OMe, SiMe3, SnMe3, PbMe3, HgOAc) were recorded. After assignment of signals arising from the trans isomer, the conformational equilibrium of the cis components were determined by anal. of spectral intensities. From these the equilibrium A values of CH2R (R as before) were calculated using the counter-poise approach. The values were similar to that of Me. In the experiment, the researchers used many compounds, for example, 2-Cyclohexylacetonitrile (cas: 4435-14-7SDS of cas: 4435-14-7).
2-Cyclohexylacetonitrile (cas: 4435-14-7) belongs to nitriles. The R-C-N bond angle in and nitrile is 180° which give a nitrile functional group a linear shape. Both the carbon and the nitrogen are sp hydridized which leaves them both with two p orbitals which overlap to form the two π bond in the triple bond. Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. Both routes are green in the sense that they do not generate stoichiometric amounts of salts.SDS of cas: 4435-14-7
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts