Direct Formation of Tethered Ru(II) Catalysts Using Arene Exchange was written by Soni, Rina;Jolley, Katherine E.;Clarkson, Guy J.;Wills, Martin. And the article was included in Organic Letters in 2013.Recommanded Product: (R)-4-(1-Hydroxyethyl)benzonitrile This article mentions the following:
An ‘arene exchange’ approach was successfully applied for the 1st time to the synthesis of Ru(II)-based ‘arene-tethered diamine’ reduction catalysts, e.g., I, directly from their ligands in one step. This provides an alternative method for the formation of known complexes, and a route to novel complexes. The novel complexes are highly active in both asym. transfer and pressure hydrogenation of ketones. E.g., reaction of acetophenone with catalyst I in HCO2H/Et3N solution at 60° to give quant. yield of (R)-1-phenylethanol. In the experiment, the researchers used many compounds, for example, (R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6Recommanded Product: (R)-4-(1-Hydroxyethyl)benzonitrile).
(R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6) belongs to nitriles. There has been no report on the microbial biosynthesis of nitriles and the physiological function of such enzymes, nor was it not even known whether aliphatic and aromatic nitriles are biological compounds or just petrochemicals. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Recommanded Product: (R)-4-(1-Hydroxyethyl)benzonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts