A cost-effective and green aqueous synthesis of 3-substituted coumarins catalyzed by potassium phthalimide was written by Kiyani, Hamzeh;Daroonkala, Masoumeh Darzi. And the article was included in Bulletin of the Chemical Society of Ethiopia in 2015.Related Products of 51473-74-6 This article mentions the following:
An efficient procedure for the synthesis of various 3-substituted coumarins I [R = H, 6-Br, 7-NEt2, 8-OMe; R1 = CN, COOH; X = O] as well as 2-imino-2H-chromenes I [R1 = CN; X = NH] was developed via potassium phthalimide-catalyzed Knoevenagel condensation reaction of salicylaldehydes with active methylene compounds under aqueous conditions at room temperature This approach provided many merits such as high yields of products, simple work-up procedure, waste free and mild reaction conditions, com. available organocatalyst and the use of water as environmentally benign solvent. In the experiment, the researchers used many compounds, for example, 7-(Diethylamino)-2-oxo-2H-chromene-3-carbonitrile (cas: 51473-74-6Related Products of 51473-74-6).
7-(Diethylamino)-2-oxo-2H-chromene-3-carbonitrile (cas: 51473-74-6) belongs to nitriles. The electronic structure of nitriles is very similar to that of an alkyne with the main difference being the presence of a set of lone pair electrons on the nitrogen. Some nitriles are manufactured by heating carboxylic acids with ammonia in the presence of catalysts. This process is used to make nitriles from natural fats and oils, the products being used as softening agents in synthetic rubbers, plastics, and textiles and for making amines.Related Products of 51473-74-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts