Fungal hydroxylation of ethyl benzene and derivatives was written by Holland, Herbert L.;Carter, Ian M.;Chenchaiah, P. Chinna;Khan, Shaheer H.;Munoz, Benito;Ninniss, Ronald W.;Richards, Denise. And the article was included in Tetrahedron Letters in 1985.Formula: C9H9NO This article mentions the following:
The fungus Mortierella isabellina converted Et benzene and a number of para-substituted derivatives to the corresponding optically active 1-phenylethanols with enantiomeric excesses of 5-40%. H removal from the substrate precedes product formation and is stereochem. independent of it. In the experiment, the researchers used many compounds, for example, (R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6Formula: C9H9NO).
(R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6) belongs to nitriles. Nitrile compounds can be prepared by the incorporation of a cyanide source through C–C bond formation or by dehydration of primary carboxamides. Asymmetric bioreduction of nitriles is an attractive route to produce optically active nitriles as current metal-catalyzed hydrogenations tend to have low reactivity.Formula: C9H9NO
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts