Straightforward conversion of arene carboxylic acids into aryl nitriles by palladium-catalyzed decarboxylative cyanation reaction was written by Ouchaou, Kahina;Georgin, Dominique;Taran, Frederic. And the article was included in Synlett in 2010.Reference of 55406-13-8 This article mentions the following:
A one-pot procedure to convert aromatic carboxylic acids into aromatic nitriles was described. The methodol. is based on a palladium(II)-catalyzed decarboxylative cyanation reaction using cyanohydrins as soluble cyanide sources. The described reaction worked on a panel of substrates and is addnl. of particular interest for the straightforward preparation of 13C- or 14C-labeled compounds In the experiment, the researchers used many compounds, for example, 3-Methylthiophene-2-carbonitrile (cas: 55406-13-8Reference of 55406-13-8).
3-Methylthiophene-2-carbonitrile (cas: 55406-13-8) belongs to nitriles. Nitrile compounds can be prepared by the incorporation of a cyanide source through C–C bond formation or by dehydration of primary carboxamides. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Reference of 55406-13-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts