Related Products of 51762-67-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 51762-67-5, name is 3-Nitrophthalonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
3-nitrophthalonitrile (20 mmol) and 2,4,6-tris(dimethylaminomethyl)-phenol (20-70 mmol, preferably 60 mmol) as reactants, dimethyl sulfoxide (40) -200 mL, preferably 140 mL, is the solvent, and the reaction is stirred at room temperature ~ 60C (preferably 60C) for 24 to 72 hours in the presence of potassium carbonate (30 to 90 mmol, preferably 80 mmol) and nitrogen, and monitored by thin layer chromatography. Should be filtered to remove the reaction mixture was insoluble potassium carbonate, evaporated to dryness, adding 50 ~ 100mL of chloroform, stirred and filtered to remove insolubles, evaporated to dryness, add 50 ~ 100mL of water to the solid and 15 ~ 45mL HCl (1mol/L) stirred and filtered to remove insolubles. NaOH was added to the filtrate. The solids were precipitated and filtered. The solids were washed with water and dried in vacuo at 50C to give 3-(2,4,6-tris(dimethylamino). Methyl)-phenoxy)phthalonitrile, yield 64%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Nitrophthalonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Fuzhou University; Huang Jiandong; Peng Xiaohui; Zheng Bingde; (25 pag.)CN107915740; (2018); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts