Synthetic Route of 53312-81-5, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 53312-81-5, Name is 5-Amino-2-fluorobenzonitrile, SMILES is NC1=CC(=C(C=C1)F)C#N, belongs to nitriles-buliding-blocks compound. In a article, author is Chen, Zan, introduce new discover of the category.
Copper-promoted cyanoalkylation/ring-expansion of vinylcyclopropanes with alpha-C-H bonds in alkylnitriles toward 3,4-dihydronaphthalenes
A copper-promoted oxidative cyanomethylation/ring-expansion of vinylcyclopropanes with alpha-C(sp(3))-H bonds in alkyl nitriles is established for the generation of 1-cyanoethylated 3,4-dihydronaphthalenes. This cyanomethylation/ring-expansion involves a radical pathway and proceeds via cyanomethyl radical formation, radical addition and ring-expansion. This ring-expansion strategy offers a highly atom-economical route for the construction of nitrile-containing 3,4-dihydronaphthalenes, which can be transformed into other useful products under simple conditions.
Synthetic Route of 53312-81-5, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 53312-81-5 is helpful to your research.