Application of 4426-11-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4426-11-3, name is Cyclobutanecarbonitrile, This compound has unique chemical properties. The synthetic route is as follows.
(a) A solution of borane-tetrahydrofuran complex [(1M] in tetrahydrofuran, [120ML)] was added over [10MIN] to a solution of cyclobutane carbonitrile (8. [1G)] [Lancaster] in dry tetrahydrofuran [(20ML)] under nitrogen at room temperature. The solution was refluxed overnight then cooled to [20.] Methanol [(150ML)] was added dropwise over 15mins keeping the temperature below [25,] then the mixture was cooled to [0 AND] dry hydrogen chloride was bubbled through for 30min. The resulting mixture was refluxed for 90min, evaporated and the residue re-evaporated twice from methanol. Ether [(150ML)] was added and the resulting solid was filtered off. It was taken up in hot isopropanol [(50ML),] filtered, and hot acetonitrile [(30ML)] added. The mixture was cooled and the solid filtered off to give the [C-CYCLOBUTYLMETHYLAMINE] hydrochloride (5.7g) NMR (400 MHz, DMSO-d6) F6382 1.8 (4H, m), 2.0 (2H, m), 2.54 [(1H,] m), 2.80 (2H, d), 8.0 (3H, [BR S).]
The chemical industry reduces the impact on the environment during synthesis Cyclobutanecarbonitrile. I believe this compound will play a more active role in future production and life.