Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1009-35-4, name is 4-Fluoro-3-nitrobenzonitrile, A new synthetic method of this compound is introduced below., Product Details of 1009-35-4
A mixture of 4-fluoro-3-nitrobenzonitrile (1 .0 g; 6.02 mmol), 0.502 ml (6.62 mmol) of 3- amino-propan-1 -ol and 1 .15 ml (6.62 mmol) of diisopropylethylamine in 5 ml THF is stirred at rt for 1 hr (temperature raises somewhat at the beginning). After concentration in vacuo the residue is dissolved in 50 ml of ethyl acetate, washed with 50 ml of 4percent aqueous sodium hydrogen carbonate and brine, dried and concentrated. 1 .32 g of pure title compound as a solid are thus obtained (99 percent yield).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.