1897-41-2, name is 2,3,5,6-Tetrachloroterephthalonitrile, belongs to nitriles-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. name: 2,3,5,6-Tetrachloroterephthalonitrile
Comparative Example 3 Preparation of 2,3,5,6-tetrachloro-1,4-benzenedicarboxylic acid (compound 2) from 2,3,5,6-tetrachloro-1,4-benzenedicarbonitrile (compound 3) 5.32 g (0.02 mol) of 2,3,5,6-tetrachloro-1,4-benzenedicarbonitrile and 17.65 g of 90.0percent sulfuric acid were charged into a reactor, and a hydrolysis of 2,3,5,6-tetrachloro-1,4-benzenedicarbonitrile was performed under atmospheric pressure. The temperature and reaction time were as specified in Table 1. After the completion of the reaction, the same processing as in Example 1 was conducted. As a result, 2,3,5,6-tetrachloro-1,4-benzenedicarboxylic acid was obtained. Yield: 5.9 g (isolation yield 97percent), and IR (KBr):
The synthetic route of 1897-41-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SDS Biotech K.K.; US2001/25121; (2001); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts