Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Reference of 20099-89-2.
Gui, Qing-Wen;Wang, Bin-Bin;Zhu, Sha;Li, Fu-Long;Zhu, Meng-Xue;Yi, Min;Yu, Jia-Ling;Wu, Zhi-Lin;He, Wei-Min research published 《 Four-component synthesis of 3-aminomethylated imidazoheterocycles in EtOH under catalyst-free, oxidant-free and mild conditions》, the research content is summarized as follows. With green ethanol as the sole solvent, 3-aminomethylated imidazoheterocycles I [R1 = H, 6-Me, 7-Me, etc.; R2 = Ph, 4-ClC6H4, 2-furanyl, etc.; R3 = Bn, n-Bu, CH2CH2CN, etc.; R4 = H, Me, i-Pr, etc.; R3R4 = CH2(CH2)2CH2, CH2(CH2)CH2, CH2CH2OCH2CH2, R3 = R4 = Et, i-Pr] were synthesized via a four-component reaction of 2-aminopyridines with 2-bromoacetophenones dichloromethane and amines at ambient temperature under metal-free, oxidant-free and mild conditions.
Reference of 20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts