In 2005,Albrecht, Uwe; Goerdes, Dirk; Schmidt, Enrico; Thurow, Kerstin; Lalk, Michael; Langer, Peter published 《Synthesis and structure-activity relationships of 2-alkylidenethiazolidine-4,5-diones as antibiotic agents》.Bioorganic & Medicinal Chemistry published the findings.Computed Properties of C8H6BrN The information in the text is summarized as follows:
2-Alkylidenethiazolidine-4,5-diones were prepared by novel one-pot cyclizations of arylacetonitriles with isothiocyanates and Et 2-chloro-2-oxoacetate. The products show antibiotic activity against the Gram-pos. bacteria Bacillus subtilis and Staphylococcus aureus. The results came from multiple reactions, including the reaction of 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Computed Properties of C8H6BrN)
According to other reports, 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) is used in the preparation of diarylpyrimidines (DAPYs) as HIV-1 non-nucleoside reverse transcriptase inhibitors.Computed Properties of C8H6BrN
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts