Recommanded Product: 2-(3-Bromophenyl)acetonitrileIn 2020 ,《Synthesis and Antibacterial and Antifungal Activity of New Thieno[2,3-d]Pyrimidin-4(3H)-One Derivatives》 was published in Pharmaceutical Chemistry Journal. The article was written by Kahveci, B.; Dogan, I. S.; Mentese, E.; Sellitepe, H. E.; Kart, D.. The article contains the following contents:
A series of new 2-(4/3-substitutedbenzyl)thieno[2,3-d]pyrimidin-4(3H)-ones and 2-(4/3-substituted benzyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one derivatives I [R = 4-Me, 3-Me, 4-Cl, 3-Cl, 4-Br, 3-Br; R1 = R2 = H; R1R2 = (CH2)4] were synthesized for the first time by the reaction of corresponding 2-aminothiophene-3-carboxamide derivatives II and appropriate iminoester hydrochlorides RC6H4CH2C(OCH2CH3)=NH.HCl under suitable conditions. In these tests, compounds I [R = 4-Me, 3-Me, 4-Cl, 3-Cl, 4-Br, 3-Br; R1R2 = (CH2)4] showed higher antifungal activity than fluconazole against Candida fungus species. The 2-substituted thieno-[2,3-d]pyrimidin-4(3H)-ones I (R1 = R2 = H) showed better antibacterial activity than 2-substituted 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one derivatives I [R1R2 = (CH2)4]. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Recommanded Product: 2-(3-Bromophenyl)acetonitrile)
2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) has been used in the synthesis of a series of aminoethylbiphenyls, novel 5-HT7 receptor ligands or 2-(1-cyano-1-(3-bromophenyl))methylidene-3-phenylthiazolidine-4,5-dione.Recommanded Product: 2-(3-Bromophenyl)acetonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts