Xing, Ai-Ping; Shen, Zhenpeng; Zhao, Zhe; Tian, Xinzhe; Ren, Yun-Lai published their research in Catalysis Communications in 2021. The article was titled 《CuO-catalyzed conversion of arylacetic acids into aromatic nitriles with K4Fe(CN)6 as the nitrogen source》.Application of 1194-02-1 The article contains the following contents:
CuO was demonstrated to be effective as the catalyst for the conversion of arylacetic acids to aromatic nitriles ArCN [Ar = Ph, 2-MeC6H4, 1-naphthyl, etc.] with non-toxic and inexpensive K4Fe(CN)6 as the nitrogen source via the complete cleavage of the C≡N triple bond. The present method allowed a series of arylacetic acids including phenylacetic acids, naphthaleneacetic acids, 2-thiopheneacetic acid and 2-furanacetic acid to be converted into the targeted products in low to high yields. The experimental process involved the reaction of 4-Fluorobenzonitrile(cas: 1194-02-1Application of 1194-02-1)
4-Fluorobenzonitrile(cas: 1194-02-1) is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.Application of 1194-02-1
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts