Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Name: Methyl 2-cyanoacetate.
Jackson, Grayson L.;Dennis, Joseph M.;Dolinski, Neil D.;van der Naald, Michael;Kim, Hojin;Eom, Christopher;Rowan, Stuart J.;Jaeger, Heinrich M. research published ã?Designing Stress-Adaptive Dense Suspensions Using Dynamic Covalent Chemistryã? the research content is summarized as follows. The non-Newtonian behaviors of dense suspensions are central to their use in technol. and industrial applications and arise from a network of particle-particle contacts that dynamically adapt to imposed shear. Reported herein are studies aimed at exploring how dynamic covalent chem. between particles and the polymeric solvent can be used to tailor such stress-adaptive contact networks, leading to their unusual rheol. behaviors. Specifically, a room temperature dynamic thia-Michael bond is employed to rationally tune the equilibrium constant (Keq) of the polymeric solvent to the particle interface. It is demonstrated that low Keq leads to shear thinning, while high Keq produces antithixotropy, a rare phenomenon where the viscosity increases with shearing time. It is proposed that an increase in Keq increases the polymer graft d. at the particle surface and that antithixotropy primarily arises from partial debonding of the polymeric graft/solvent from the particle surface and the formation of polymer bridges between particles. Thus, the implementation of dynamic covalent chem. provides a new mol. handle with which to tailor the macroscopic rheol. of suspensions by introducing programmable time dependence. These studies open the door to energy-absorbing materials that not only sense mech. inputs and adjust their dissipation as a function of time or shear rate but also can switch between these two modalities on demand.
Name: Methyl 2-cyanoacetate, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts