Jivani, A. J. team published research in Russian Journal of Organic Chemistry in 2021 | 20099-89-2

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., SDS of cas: 20099-89-2

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. SDS of cas: 20099-89-2.

Jivani, A. J.;Kapadiya, K. M.;Khunt, R. C. research published ã€?Polar Solvent-Mediated Synthesis of Terminal Alkyne Derivatives of Thiazoles and Evaluation of Their Antidiabetic Activityã€? the research content is summarized as follows. Two new pharmacol. active series of N-alkyne-substituted indole-thiazoles, I [R = H, 4-NC, 4-Cl, etc.] and C-alkyne-substituted benzylidene-thiazoles, II [R1 = 4-Me, 4-F, 4-NC, etc.] were synthesized by a two-step procedure involving initial reactions of thiosemicarbazide with, resp., [1-(prop-2-yne-1-yloxy)-1H-indol-3-yl]formaldehyde and 2-(prop-2-yne-1-yloxy)benzaldehyde, followed by the reactions of the resulting hydrazine-1-carbothioamides with a variety of substituted phenacyl bromides. In-vitro antidiabetic activity screening by the α-amylase inhibition assay with Acarbose as a reference drug revealed an excellent antidiabetic potency in four-terminal alkyne-substituted benzylidene-and indole-thiazoles derived from dichloro- and bromophenacyl bromides.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., SDS of cas: 20099-89-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts