Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Electric Literature of 105-34-0.
Khusnutdinov, R. I.;Shchadneva, N. A.;Mayakova, Yu. Yu.;Aminov, R. I. research published ã?Condensation of Diamantan-3-one with Malononitrile and Methyl and Ethyl Cyanoacetates in the Presence of Binder-Free FeHY and NiHy Zeolitesã? the research content is summarized as follows. Binder-free iron- and nickel-containing micro-, meso-, and macroporous zeolites FeHY and NiHY were found to effectively catalyzed Knoevenagel condensation of diamantan-3-one with malononitrile, Me cyanoacetate, and Et cyanoacetate at 40°C (5 h) with 94-98% yield.
Electric Literature of 105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts