Cui, Hai-Lei; Peng, Jing; Feng, Xin; Du, Wei; Jiang, Kun; Chen, Ying-Chun published an article in 2009, the title of the article was Dual organocatalysis: asymmetric allylic-allylic alkylation of α,α-dicyanoalkenes and Morita-Baylis-Hillman carbonates.Reference of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile And the article contains the following content:
The first highly enantioselective allylic-allylic alkylation of α,α-dicyanoalkenes I (RR1 = 2-C6H4SCH2, 2-C6H4OCH2; R = 2-thienyl, R1 = H; etc) and Morita-Baylis-Hillman carbonates II (R2 = 4-ClC6H4, E = CO2Me; R2 = Ph, E = CN; etc.) by dual catalysis of (DHQD)2AQN and (S)-BINOL was investigated. Excellent stereoselectivities were achieved for a broad spectrum of substrates (d.r. > 99:1, up to 99% ee). The multifunctional allylic products, e.g., III (RR1 = 2-C6H4SCH2, R2 = 4-ClC6H4, E = CO2Me) could be efficiently converted to a range of complex chiral cyclic frameworks. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Reference of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile
The Article related to cyano alkene asym allylic alkylation carbonate cinchona alkaloid catalyst, diene dinitrile stereoselective preparation intramol michael, asym cyano cyclohexene preparation, cinchona alkaloid binol preparation asym allylic alkylation dual catalysis and other aspects.Reference of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts