Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Application In Synthesis of 105-34-0.
Lopes, Diogo;Costa, Marta;Loucano, Joao;Proenca, Fernanda research published 《 A Convenient One-pot Synthesis of Chromenyl Acrylates and Acrylonitriles》, the research content is summarized as follows. 2H-Oxo-chromenyl acrylates I (R1 = H, OH, OMe; R2 = H, Me, Br; R3 = Me, Et) and 2H-imino-chromenyl acrylonitriles II (R1 = H, Me, OMe; R2 = H; R3 = H, Me, OH, OMe, Cl, Br) have been prepared from a salicylaldehyde and Et cyanoacetate or 2-amino-1,1,3-tricyanopropene, resp. The reaction occurs in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) and the products were isolated in good to quant. yields. Despite the simplicity of the synthesis, this is the first time that these substituted chromenes have been isolated.
105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., Application In Synthesis of 105-34-0
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts