Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Recommanded Product: 4-Nitrophthalonitrile.
Mantareva, Vanya;Kussovski, Vesselin;Orozova, Petya;Angelov, Ivan;Durmus, Mahmut;Najdenski, Hristo research published 《 Palladium Phthalocyanines Varying in Substituents Position for Photodynamic Inactivation of Flavobacterium hydatis as Sensitive and Resistant Species》, the research content is summarized as follows. Antimicrobial photodynamic therapy (aPDT) has been considered as a promising methodol. to fight the multidrug resistance of pathogenic bacteria. The procedure involves a photoactive compound (photosensitizer), the red or near IR spectrum for its activation, and an oxygen environment. In general, reactive oxygen species are toxic to biomols. which feature a mechanism of photodynamic action. The present study evaluates two clin. isolates of Gram-neg. Flavobacteriumhydatis (F. hydatis): a multidrug resistant (R) and a sensitive (S) strain. Both occur in farmed fish, leading to the big production losses because of the inefficacy of antibiotics. Palladium phthalocyanines (PdPcs) with methylpyridiloxy groups linked peripherally (pPdPc) or non-peripherally (nPdPc) were studied with full photodynamic inactivation for 5.0 μM nPdPc toward both F. hydatis, R and S strains (6 log), but with a half of this value (3 log) for 5.0 μM pPdPc and only for F. hydatis, S. In addition to the newly synthesized PdPcs as a “pos. control” was applied a well-known highly effective zinc phthalocyanine (ZnPcMe). ZnPcMe showed optimal photocytotoxicity for inactivation of both F. hydatis R and S. The present study is encouraging for a further development of aPDT with phthalocyanines as an alternative method to antibiotic medication to keep under control the harmful pathogens in aquacultures′ farms.
31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., Recommanded Product: 4-Nitrophthalonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts