Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Recommanded Product: Methyl 2-cyanoacetate.
Monterde, Cristina;Pintado-Sierra, Mercedes;Navarro, Rodrigo;Sanchez, Felix;Iglesias, Marta research published 《 Effective approach toward conjugated porous organic frameworks based on phenanthrene building blocks: metal-free heterogeneous photocatalysts》, the research content is summarized as follows. This paper reports a simple approach for the preparation of new photo-active conjugated porous polymers (CPPs) based on phenanthrene building blocks with a high Brunauer-Emmett-Teller (BET) surface area. Starting from 2,7-diiodophenanthrene-9,10-dione and its bis-dioxolane derivative with different alkynyl comonomers, we prepared a series of CPPs by C-C Sonogashira-Hagihara coupling activated by microwaves. Moreover, we demonstrated that these functionalized CPPs after hydrolysis to the corresponding diketones show much higher BET surface areas than those obtained directly from the phenanthrene-9,10-dione monomer. Reaction of diketone-hydrolyzed polymers with 2,4-difluoro-6-hydroxybenzaldehyde yields phenantroimidazole derivatives Indeed, these structurally robust polymers result in efficient, recyclable, heterogeneous photo-organocatalysts for the aza-Henry reaction (C-H functionalization) induced by visible-light irradiation
Recommanded Product: Methyl 2-cyanoacetate, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts