Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Formula: C9H6BrNO.
Sen, Partha Pratim;Roy, Vishal Jyoti;Raha Roy, Sudipta research published 《 Metal-free regioselective bromination of imidazo-heteroarenes: the dual role of an organic bromide salt in electrocatalysis》, the research content is summarized as follows. An electrochem. transformation was represented by demonstrating the dual role of an organic bromide salt, i.e., tetra-n-butylammonium bromide (TBAB), as a brominating agent and as an electrolyte for the regioselective bromination of several imidazo heteroaromatic motifs, e.g., I. Instead of using a transition metal/external oxidant, this methodol. utilized electron holes and electrons by means of anodic oxidation and cathodic reduction to form the desired products in good to excellent yields at ambient temperature The method was simple, environment friendly and compatible with various functional groups. The significance of this sustainable greener bromination technique relies on the fact that the readily available cost-effective electrodes (C(+)/C(-)) could be reused up to forty times without loss of any electrochem. activities. The electro-oxidative method could efficiently be scaled up and can be extended to chlorination as well. Moreover, this electro-synthetic strategy was extrapolated to the domino organo-electrochem. bromination technique for the synthesis of a brominated imidazo heteroaromatic moiety directly starting from substituted 2-bromoacetophenone and 2-aminopyridine by using catalytic amounts of electrolyte.
Formula: C9H6BrNO, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts